HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178498455, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Pyrazole-4-carboxylic acid | HCID 3015937 | — |
| Product | HCID 178498455 | HCID 178498455 | 90% |
Reaction Steps
10 mL of methanol at 0° C. was treated dropwise with lmL acetyl chloride, followed by addition of 2.0 g(17.84 mmol) of 4-pyrazolcarboxylic acid, followed by warming the mixture at reflux for 18 h. The solution was cooled and concentrated in vacuo to afford 2.6 g(90%) of the title compound as a white solid. 1H NMR (CD3OD) δ8.25, 3.86.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06124334 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-872b31d9a7b542ba8f669274112e8122 |
| Source note | uspto-grants-2000_09 |