HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-(4-Fluorobenzyl)-1-(2-(2-hydroxynaphth-6-oxy)ethyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(4-Fluoro-benzyl)-piperidine | HCID 3699841 | — |
| Reactant | 2-Benzyloxy-6-(2-bromo-ethoxy)-naphthalene | HCID 23294345 | — |
| Product | 4-(4-Fluorobenzyl)-1-(2-(2-hydroxynaphth-6-oxy)ethyl)piperidine | HCID 23294236 | — |
Reaction Steps
The title compound was prepared from 4-(4-Fluoro-benzyl)-piperidine and 2-benzyloxy-6-(2-bromo-ethoxy)-naphthalene and potassium carbonate in two steps as a solid, mp184-185° C. Analysis calculated for C24H26FNO2 : C, 75.96; H, 6.91; N, 3.69; F, 5.01. Found: C, 75.52; H, 6.86; N, 3.50; F, 5.15.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06124323 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-b630f12d570c43a08150f70f7ea58602 |
| Source note | uspto-grants-2000_09 |