tert-Butanol → HCID 19070340, compound

HRID 1955501Notes

Reaction equation

HRID 1955501 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([N+]([O-])=O)[C:4]=1[C:12]#[N:13])#[N:2].[C:14]([OH:18])([CH3:17])([CH3:16])[CH3:15]>>[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:18][C:14]([CH3:17])([CH3:16])[CH3:15])[C:4]=1[C:12]#[N:13])#[N:2]

Participants

3

Reactant 2

HCID 6386tert-ButanolHCID 1626521,2-Benzenedicarbonitrile, 3-nitro-

Product 1

HCID 19070340HCID 19070340, compoundYield 70%

Procedure

As in Synthesis Example 1 but using 1.73 grams of 1,2-dicyano-3-nitrobenzene and 2.20 grams of t-butylalcohol, there was obtained 1.40 grams of 1,2-dicyano-3-t-butoxybenzene (yield of 70%). Next, as in Synthesis Example 1 but using 1.40 grams of this benzene compound and 0.58 gram of BBr3, there was obtained 2.9 grams of the end product (yield 60%, mp 184°-186° C.).

Workup

  1. customAs in Synthesis Example 1

Sources & evidence

ORD record
ord-9cc55b70107143f6ba1c1477386ca616
Source dataset
uspto-grants-1998_07
Patent number
US05776656

Reaction notes

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