Hydrochloric Acid → HCID 131720752, compound

HRID 1955614Notes

Reaction equation

HRID 1955614 reaction equation
C([N:8]1[CH2:13][CH2:12][CH:11]([N:14]2[CH2:18][CH:17]([CH2:19][N:20]3[CH2:25][CH2:24][N:23]([CH2:26][CH2:27][C:28]([O:30][CH3:31])=[O:29])[CH2:22][CH2:21]3)[O:16][C:15]2=[O:32])[CH2:10][CH2:9]1)(OC(C)(C)C)=O.[ClH:33]>>[ClH:33].[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]2[CH2:18][CH:17]([CH2:19][N:20]3[CH2:25][CH2:24][N:23]([CH2:26][CH2:27][C:28]([O:30][CH3:31])=[O:29])[CH2:22][CH2:21]3)[O:16][C:15]2=[O:32])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 15340895HCID 15340895, compound

Product 1

HCID 131720752HCID 131720752, compound

Procedure

0.6 g of 3-(1-BOC-4-piperidyl)-5-[4-(2-methoxycarbonylethyl)piperazino]methyloxazolidin-2-one [obtainable according to Ex. 1] are suspended in 40 ml of 2N HCl solution based on dioxane and the mixture is stirred at room temperature for 3 hours. After removal of the solvent and customary working up, 3-(4-piperidyl)-5-[4-(2-methoxycarbonylethyl)piperazino]methyloxazolidin-2-one, hydrochloride, is obtained.

Workup

  1. customAfter removal of the solvent

Sources & evidence

ORD record
ord-42f6f300bf0e45b4a0965df8667b86af
Source dataset
uspto-grants-1998_07
Patent number
US05776937

Reaction notes

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