HRID1955623

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Nc1c(N)n(CC2CCCCC2)c(=O)n(CC2CCCCC2)c1=O

HCID22244975

未命名化合物

HCID23247180

未命名化合物

PRODUCTS

生成物

结构：COC(=O)/C=C/c1ccc(-c2nc3c(=O)n(CC4CCCCC4)c(=O)n(CC4CCCCC4)c3[nH]2)cc1

HCID178499795

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

(E)-Methyl 4-(dimethoxymethyl)cinnamate (from step (a)) was used in place of 4-formylcinnamic acid in the procedure described in step (d) of Example 1, except that a drop of acetic acid was added during the formation of the Schiff base with 1,3-bis(cyclohexylmethyl)-5,6-diaminouracil. Title compound was formed as a white powder, m.p. >270° C.; 1H-NMR (DMSO-d6) consistent with structure.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d70e95ffe9e6466a86212f1b31b8ec61
来源数据集: uspto-grants-1998_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05776940
来源说明: uspto-grants-1998_07

反应 SMILES

CO[CH:3](OC)[C:4]1[CH:15]=[CH:14][C:7](/[CH:8]=[CH:9]/[C:10]([O:12][CH3:13])=[O:11])=[CH:6][CH:5]=1.[CH:18]1([CH2:24][N:25]2[C:32]([NH2:33])=[C:31]([NH2:34])[C:29](=[O:30])[N:28]([CH2:35][CH:36]3[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]3)[C:26]2=[O:27])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>C(O)(=O)C>[CH:36]1([CH2:35][N:28]2[C:29](=[O:30])[C:31]3[N:34]=[C:3]([C:4]4[CH:5]=[CH:6][C:7](/[CH:8]=[CH:9]/[C:10]([O:12][CH3:13])=[O:11])=[CH:14][CH:15]=4)[NH:33][C:32]=3[N:25]([CH2:24][CH:18]3[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[C:26]2=[O:27])[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]1