HCID 18624522, compound → HCID 19071308, compound

HRID 1955629Notes

Reaction equation

HRID 1955629 reaction equation
[CH:1]1([CH2:8][NH:9][C:10]([NH:12][CH2:13][CH:14]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)=[O:11])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:21][C:22]1N(CC2CCCC2)C(=O)N(CC2CCCC2)[C:24](=[O:41])[CH:23]=1>>[NH2:21][C:22]1[N:9]([CH2:8][CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]2)[C:10](=[O:11])[N:12]([CH2:13][CH:14]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)[C:24](=[O:41])[CH:23]=1

Participants

3

Reactant 2

HCID 18624522HCID 18624522, compoundHCID 19071300HCID 19071300, compound

Product 1

HCID 19071308HCID 19071308, compound

Procedure

In the manner of step (b) of Example 1, 1,3-bis(cycloheptylmethyl)urea (from step (a), 3.99 g, 14.23 mmol) was converted to 6-amino-1,3-bis(cyclopentylmethyl)uracil (3.22 g, 65%), m.p. 194°-197° C.; 1H-NMR (DMSO-d6) consistent with structure.

Sources & evidence

ORD record
ord-f478270d89d84ea2ad759125de5b7e2f
Source dataset
uspto-grants-1998_07
Patent number
US05776940

Reaction notes

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