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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1955663Generated: November 1, 2026

4-Chloropyridine hydrochloride → (2-Methyl-indol-1-yl)-pyridin-4-yl-amine

https://huagongshe.com/reaction/1955663

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloropyridine hydrochlorideHCID 81852—
Reactant2-Methyl-1H-indol-1-amineHCID 12427291—
Product(2-Methyl-indol-1-yl)-pyridin-4-yl-amineHCID 10799122—

Reaction Steps

The title compound was prepared from 2-methyl-1H-indol-1-amine and 4-chloropyridine hydrochloride at 120° C. for 30 minutes in substantially the same manner as in Example 17, m.p. 75°-78° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05776955
Source datasetuspto-grants-1998_07
ORD IDord-b56b22af59ac4d6f92ee79644e616718
Source noteuspto-grants-1998_07