4-Chloropyridine hydrochloride → (2-Methyl-indol-1-yl)-pyridin-4-yl-amine

HRID 1955663Notes

Reaction equation

HRID 1955663 reaction equation
[CH3:1][C:2]1[N:3]([NH2:11])[C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.Cl.Cl[C:14]1[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=1>>[CH3:1][C:2]1[N:3]([NH:11][C:14]2[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=2)[C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2

Participants

3

Reactant 2

HCID 818524-Chloropyridine hydrochlorideHCID 124272912-Methyl-1H-indol-1-amine

Product 1

HCID 10799122(2-Methyl-indol-1-yl)-pyridin-4-yl-amine

Procedure

The title compound was prepared from 2-methyl-1H-indol-1-amine and 4-chloropyridine hydrochloride at 120° C. for 30 minutes in substantially the same manner as in Example 17, m.p. 75°-78° C.

Sources & evidence

ORD record
ord-b56b22af59ac4d6f92ee79644e616718
Source dataset
uspto-grants-1998_07
Patent number
US05776955

Reaction notes

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