Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070, compound

HRID 1956138Notes

Reaction equation

HRID 1956138 reaction equation
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

Product 1

HCID 21925070HCID 21925070, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture was concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

Workup

  1. concentrationthe reaction mixture was concentrated to dryness
  2. customthe residue was dried in vacuo

Sources & evidence

ORD record
ord-f913dbfa3e214cbcb400c563c7d8088b
Source dataset
uspto-grants-1998_07
Patent number
US05780454

Reaction notes

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