HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → HCID 22375413, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 6-Ethoxy-2,3-dihydro-1H-inden-1-one | HCID 15039152 | — |
| Catalyst | Titanium isopropoxide | HCID 11026 | — |
| Product | HCID 22375413 | HCID 22375413 | — |
Reaction Steps
Piperazine (19.8 g, 0.23 mol), 6-ethoxyindan-1-one (4.00 g, 23 mmol), titanium(IV) isopropoxide (15.3 ml, 46 mmol) and sodium borohydride (2.7 g, 71 mmol) were reacted by Method A to give the product which was converted to the fumurate salt (beige solid, 5.7 g, 68.5%, mp: 142°-147° C.). Calcd for C15H22N2O.C4H4O4 : C, 62.97%; H, 7.23%; N, 7.73%. Found: C. 62.88%; H, 7.22%; N, 7.48%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780470 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-75db16f29d95429baf1d8cb9f788df60 |
| Source note | uspto-grants-1998_07 |