1-(4-Fluorophenyl)piperazine → HCID 18663108, compound

HRID 1956199Notes

Reaction equation

HRID 1956199 reaction equation
C1(O[C:8](=[O:21])[NH:9][C:10]2[C:11]([O:19][CH3:20])=[N:12][C:13]([CH3:18])=[C:14]([CH2:16][CH3:17])[CH:15]=2)C=CC=CC=1.[F:22][C:23]1[CH:28]=[CH:27][C:26]([N:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)=[CH:25][CH:24]=1>>[CH2:16]([C:14]1[CH:15]=[C:10]([NH:9][C:8]([N:32]2[CH2:31][CH2:30][N:29]([C:26]3[CH:25]=[CH:24][C:23]([F:22])=[CH:28][CH:27]=3)[CH2:34][CH2:33]2)=[O:21])[C:11]([O:19][CH3:20])=[N:12][C:13]=1[CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 752601-(4-Fluorophenyl)piperazineHCID 19357010Phenyl N-(5-ethyl-2-methoxy-6-methylpyridin-3-yl)carbamate

Product 1

HCID 18663108HCID 18663108, compoundYield 81%

Procedure

Phenyl-N-(5-ethyl-2-methoxy-6-methylpyridin 3-yl)carbamate and 1-(4-fluorophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Sources & evidence

ORD record
ord-46b33a65e72c45e697ae0e6450728aec
Source dataset
uspto-grants-1998_07
Patent number
US05780472

Reaction notes

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