HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-{2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperazin-1-yl]ethyl}-3-ethylimidazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | 1-{2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperid-1-yl]ethyl}-3-isopropylimidazolidin-2-one | HCID 10926854 | — |
| Reactant | HCID 19805377 | HCID 19805377 | — |
| Product | 1-{2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperazin-1-yl]ethyl}-3-ethylimidazolidin-2-one | HCID 18663202 | — |
Reaction Steps
This product is prepared in the same manner as the compound of Example 1 but using 4-(6-fluoro-1,2-benzisoxazol-3-yl)piperazine instead of 4-(6-fluoro-1,2-benzisoxazol-3-yl)-piperidine in Step 1, and using bromoethane instead of 2-bromopropane in Step 2. The hydrochloride of the title compound so obtained melts at 201°-204° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780474 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-a80eeb76fe8c4f4c971cfb86a5cf5390 |
| Source note | uspto-grants-1998_07 |