Phenyl isocyanate → HCID 22390756, compound

HRID 1956355Notes

Reaction equation

HRID 1956355 reaction equation
[NH:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4].[C:8]1([N:14]=[C:15]=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>C(Cl)Cl>[CH:11]1[CH:12]=[CH:13][C:8]([NH:14][C:15]([N:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4])=[O:16])=[CH:9][CH:10]=1

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 8113Diethanolamine

Product 1

HCID 22390756HCID 22390756, compoundYield 119.7%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

A mixture of 15.62 ml (0.136 mol) of diethanolamine and 163 ml of methylene chloride is poured, at a temperature of 10° C., into a three-necked flask containing 18.25 ml (0.168 mol) of phenyl isocyanate dissolved in 37 ml of CH2Cl2. The mixture is left at that temperature for one hour, and then at room temperature overnight, and concentrated in vacuo to obtain 36.5 g of the expected product. (Yield=100%).

Workup

  1. additionis poured, at a temperature of 10° C., into a three-necked flask
  2. concentrationat room temperature overnight, and concentrated in vacuo

Sources & evidence

ORD record
ord-4479d36f66b044a8b02785945fd15504
Source dataset
uspto-grants-1998_07
Patent number
US05780474

Reaction notes

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