Hydrochloric Acid → HCID 18663212, compound

HRID 1956356Notes

Reaction equation

HRID 1956356 reaction equation
[F:1][C:2]1[CH:30]=[CH:29][C:5]2[C:6]([CH:9]3[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][N:17]4[CH2:21][CH2:20][N:19]([C:22]5[CH:27]=CC=C[CH:23]=5)[C:18]4=[O:28])[CH2:11][CH2:10]3)=[N:7][O:8][C:4]=2[CH:3]=1.[C:31](N=C=O)(C)(C)C.Cl>>[F:1][C:2]1[CH:30]=[CH:29][C:5]2[C:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]4[CH2:21][CH2:20][N:19]([C:22]([CH3:31])([CH3:23])[CH3:27])[C:18]4=[O:28])[CH2:13][CH2:14]3)=[N:7][O:8][C:4]=2[CH:3]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 62412tert-Butyl isocyanateHCID 99532691-(2-(4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)-1-PIPERIDINYL)ETHYL)-3-PHENYL-2-IMIDAZOLIDINONE

Product 1

HCID 18663212HCID 18663212, compound

Procedure

This product is obtained in the same manner as the compound of Example 5, but with replacement of the phenyl isocyanate by tert-butyl isocyanate in Step 1 of the synthesis. The hydrochloride of the title compound melts at 205°-208° C.

Sources & evidence

ORD record
ord-dcab6bdaf1934d34ae8bcb5b90f8f538
Source dataset
uspto-grants-1998_07
Patent number
US05780474

Reaction notes

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