Hydrochloric Acid → HCID 18663204, compound

HRID 1956361Notes

Reaction equation

HRID 1956361 reaction equation
[F:1][C:2]1[CH:30]=[CH:29][C:5]2[C:6]([CH:9]3[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][N:17]4[CH2:21][CH2:20]N(C5C=CC=CC=5)C4=O)[CH2:11][CH2:10]3)=[N:7][O:8][C:4]=2[CH:3]=1.[Cl:31][C:32]1[CH:37]=[CH:36][CH:35]=[C:34]([Cl:38])[C:33]=1[N:39]=[C:40]=[O:41].Cl>>[F:1][C:2]1[CH:30]=[CH:29][C:5]2[C:6]([CH:9]3[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][N:17]4[CH2:21][CH2:20][N:39]([C:33]5[C:32]([Cl:31])=[CH:37][CH:36]=[CH:35][C:34]=5[Cl:38])[C:40]4=[O:41])[CH2:11][CH2:10]3)=[N:7][O:8][C:4]=2[CH:3]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 6045371,3-Dichloro-2-isocyanatobenzeneHCID 99532691-(2-(4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)-1-PIPERIDINYL)ETHYL)-3-PHENYL-2-IMIDAZOLIDINONE

Product 1

HCID 18663204HCID 18663204, compound

Procedure

This product is obtained in the same manner as the compound of Example 5, but with replacement of the phenyl isocyanate by 2,6-dichlorophenyl isocyanate in Step 1 of the synthesis. The hydrochloride of the title compound melts at 237°-241° C.

Sources & evidence

ORD record
ord-b5ea753c25394bc3be4ef7e160f43481
Source dataset
uspto-grants-1998_07
Patent number
US05780474

Reaction notes

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