Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 18663250 | HCID 18663250 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 19605591 | HCID 19605591 | — |
Reaction Steps
A solution of the above ester (10 g, 42.7 mmol) in THF (50 mL) was treated with 1N LiOH (47 mL, 47.0 mmol) and H2O (50 mL). The resulting solution was concentrated and the aqueous residue cooled to 0° C., then adjusted to pH≈6 with 1N HCl and the resulting solid 8-1, collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05780480 |
|---|
| Source dataset | uspto-grants-1998_07 |
|---|
| ORD ID | ord-82ff4110022c4127a3096d4f2dfbd88a |
|---|
| Source note | uspto-grants-1998_07 |
|---|
