Pyrrolidine → HCID 18663593, compound

HRID 1956599Notes

Reaction equation

HRID 1956599 reaction equation
Br[CH2:2][C:3]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[O:7][C:6]2[CH:14]=[CH:15][CH:16]=[C:17]([Cl:18])[C:5]=2[CH:4]=1.[NH:19]1[CH2:23][CH2:22][CH2:21][CH2:20]1>>[ClH:18].[Cl:18][C:17]1[C:5]2[CH:4]=[C:3]([CH2:2][N:19]3[CH2:23][CH2:22][CH2:21][CH2:20]3)[C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=3[O:7][C:6]=2[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 18663584HCID 18663584, compound

Product 1

HCID 18663593HCID 18663593, compoundYield 51%

Procedure

Preparation analogous to Example 2 from 10-bromomethyl-1-chloro-dibenz[b,f]oxepine with pyrrolidine. Yield: 51%, yellow foam; melting point: not determined, (yellow foam); 1H-NMR (CDCl3, 200 MHz): 1.78 (m, 4H); 2.65 (m, 4H); 3.65 (s, 2H); 7.10-7.45 (m, 7H) 7.68 (d, 1H).

Sources & evidence

ORD record
ord-cc3914fea3df4d6d8954607e3020b0b4
Source dataset
uspto-grants-1998_07
Patent number
US05780501

Reaction notes

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