HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylbenzoyl chloride → [2-(4-Methoxyphenyl)-6-methoxybenzo[b]thien-3-yl][3-methylphenyl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylbenzoyl chloride | HCID 74375 | — |
| Reactant | 6-Methoxy-2-(4-methoxyphenyl)benzo[b]thiophene | HCID 850941 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | [2-(4-Methoxyphenyl)-6-methoxybenzo[b]thien-3-yl][3-methylphenyl]methanone | HCID 17760556 | 163.5% |
Reaction Steps
In a manner similar to that described in Preparation 2, 3.1 g (20 mmol) of 3-methylbenzoylchloride, 2 g (7.4 mmol) of 2-(4-methoxyphenyl)-6-methoxybenzo[b]thiophene and 6.7 g (50 mmol) of AlCl3 were converted to 4.7 g of the title compound, isolated as yellow amorphous powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780648 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-84e9f8c6719140c688a1f085c6c2d1c5 |
| Source note | uspto-grants-1998_07 |