Dichloromethane → 2-(4-Methylpiperazin-1-yl)phenol

HRID 195694Notes

Reaction equation

HRID 195694 reaction equation
[CH3:61][N:62]1[CH2:63][CH2:64][N:65]([c:66]2[cH:67][cH:68][cH:69][cH:70][c:71]2[O:72][CH2:73][C:74]([Cl:75])=[O:76])[CH2:77][CH2:78]1.[CH:52]([N:53]([CH2:54][CH3:55])[CH:56]([CH3:57])[CH3:58])([CH3:59])[CH3:60].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:6]2[nH:7][n:8][n:9][n:10]2)[c:25]([NH:26][C:27](=[O:28])[CH2:29][O:11][c:12]2[c:13]([N:18]3[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]3)[cH:14][cH:15][cH:16][cH:17]2)[cH:30]1.[Cl:31][c:32]1[cH:33][cH:34][c:35](-[c:36]2[nH:37][n:38][n:39][n:40]2)[c:41]([NH:42][C:43](=[O:44])[c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[cH:51]1.[Cl:79][CH2:80][Cl:81]>>[OH:11][c:12]1[c:13]([N:18]2[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]2)[cH:14][cH:15][cH:16][cH:17]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 57576644HCID 57576644, compoundHCID 178480656HCID 178480656, compoundHCID 178522172HCID 178522172, compound

Product 1

HCID 158380942-(4-Methylpiperazin-1-yl)phenol

Sources & evidence

ORD record
ord-57068c6ff0994ac3bff42ed7f0b52c9d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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