HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 3-(4-(Bromomethyl)phenyl)thiophene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 3-(4-Methylphenyl)thiophene | HCID 4130347 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 3-(4-(Bromomethyl)phenyl)thiophene | HCID 13773538 | — |
Reaction Steps
To a solution of 4-(3-thienyl)toluene (3.56 g, 20.5 mmol) in carbon tetrachloride (100 ml) is added N-bromosuccinimide (3.64 g, 20.5 mol) and benzoyl peroxide (80 mg, 3.3 mmol). The reaction mixture is heated at reflux for 24 hrs. and concentrated in vacuo. The reaction mixture is recrystallized from ethanol to afford 4-(3-thienyl)benzyl bromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05780498 |
| Source dataset | uspto-grants-1998_07 |
| ORD ID | ord-ef8bed6f4a65437fb5f42700a13c9323 |
| Source note | uspto-grants-1998_07 |