Potassium Hydroxide → HCID 67674953, compound

Participants

Reaction Steps

A stirred solution of N-(3,5-dimethylbenzoyl)-N-methyl-2-methyl-3-[4-(3-thienyl)phenyl]alanine methyl ester (100 mg, 0.245 mmol) and potassium hydroxide (40 mg, 0.72 mmol) in ethanol (5 ml) is refluxed overnight. The mixture is diluted with water and washed with ether. The aqueous layer is washed with brine, dried over magnesium sulfate, and concentrated in vacuo to give the corresponding crude N-(3,5-dimethylbenzoyl)-N-methyl-2-methyl-3-[4-(3-thienyl)phenyl]alanine

Provenance & Evidence