HCID 10617092, compound → HCID 10710202, compound

Participants

Reaction Steps

6,7-Dichloro-2,3-dimethoxy-5-(1,2,4-triazol-1-ylmethyl)-quinoxaline (99 mg, 0.29 mmol) was heated in a mixture of 2M hydrochloric acid (2 mL) and dioxane (2 mL) at reflux for 3 hours. The solvent was removed under reduced pressure and the solid residue was suspended in water and filtered to give 1,4-dihydro-6,7dichloro-5-(1,2,4-triazol-1-ylmethyl)-quinoxalin-2,3-dione (60 mg, 62%) as a white solid, mp>320° C. Found: C, 39.47; H 2.49; N, 20.54. C11H7Cl2N5O2.1.25.H2O requires C, 39.48; H 2.86; N, 20.93%.

Provenance & Evidence