Acetyl chloride → HCID 19068965, compound

HRID 1957194Notes

Reaction equation

HRID 1957194 reaction equation
[C:1]([N:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]2[CH:18]=[C:19]([C:21]([O:23][CH3:24])=[O:22])[S:20][C:10]1=2)(=[O:8])[C:2]1C=CC=CC=1.S1C2NC3C(C=2C=C1C(OC)=O)=CC=CC=3.C(Cl)(=O)C.[H-].[Na+]>>[C:1]([N:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]2[CH:18]=[C:19]([C:21]([O:23][CH3:24])=[O:22])[S:20][C:10]1=2)(=[O:8])[CH3:2]

Participants

5

Reactant 4

HCID 6367Acetyl chlorideHCID 24758Sodium hydrideHCID 10681031HCID 10681031, compoundHCID 19068969HCID 19068969, compound

Product 1

HCID 19068965HCID 19068965, compound

Procedure

Preparation as described for (21) from (19) (0.5 g), acetyl chloride (0.17 g) and NaH (0.06 g) resulted in (22) (0.55 g), m.p. 179°-181° C.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-ba414eb2e81741cf85203fc21bc897ef
Source dataset
uspto-grants-1998_07
Patent number
US05783575

Reaction notes

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