Methyl Thioglycolate → HCID 849403, compound

HRID 1957204Notes

Reaction equation

HRID 1957204 reaction equation
[C:1]1([N:7]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9]([CH:16]=O)=[C:8]2Cl)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[SH:19][CH2:20][C:21]([O:23][CH3:24])=[O:22]>>[C:1]1([N:7]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9]3[CH:16]=[C:20]([C:21]([O:23][CH3:24])=[O:22])[S:19][C:8]2=3)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 16907Methyl ThioglycolateHCID 3147932-chloro-1-phenyl-1H-indole-3-carbaldehyde

Product 1

HCID 849403HCID 849403, compoundYield 79.6%

Procedure

Prepared from 1-Phenyl-2-chloroindole-3-carbaldehyde (0.90 g), K2 CO3 (1.38 g) and methyl 2-mercaptoacetate (0.55 ml) yielding (51) 0.86 g (79.6%). M.p. 147°-149° C.

Sources & evidence

ORD record
ord-ae0b0339738147deaf015c6ae6eeddfa
Source dataset
uspto-grants-1998_07
Patent number
US05783575

Reaction notes

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