反应详情

In a preparation similar to that described above for 3-chloro-2-(4-chloro-3-propargyloxyphenyl)-5-trifluoromethylpyridine, reaction of 1.4 g (4.5 mmol) of 3-chloro-2-(4-chloro-2-fluoro-5-hydroxyphenyl)-5-trifluoromethylpyridine and 0.6 g (5 mmol) of propargyl bromide resulted in 1.1 g of colorless crystals. Yield: 67%; melting point: 97°-98° C.

1. customIn a preparation similar to