HCID 54347391, compound → HCID 19069372, compound

HRID 1957342Notes

Reaction equation

HRID 1957342 reaction equation
[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[O:6][C:7]1[CH:14]=[CH:13][C:10]([CH2:11][OH:12])=[CH:9][CH:8]=1>CCCCCC.CCOC(C)=O>[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[O:6][C:7]1[CH:8]=[CH:9][C:10]([CH:11]=[O:12])=[CH:13][CH:14]=1

Participants

3

Reactant 1

HCID 54347391HCID 54347391, compound

Product 1

HCID 19069372HCID 19069372, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using the alcohol prepared above and the procedures described in Example 84E, except chromatography using 4:1 hexane-EtOAc was used for purification, provided 4-(thiazol-2-yloxy)benzaldehyde. 1H NMR (CDCl3) δ10.00 (s, 1H), 7.95 (m, 2H), 7.46 (m, 2H), 7.30 (d, 1H), 6.95 (d, 1H). MS (DCl/NH3) (M+H)+ 206 and (M+H+NH3)+ 223.

Workup

  1. customprepared above and the procedures
  2. customwas used for purification

Sources & evidence

ORD record
ord-008a5b366ced45e5b5e15f0af330ec28
Source dataset
uspto-grants-1998_07
Patent number
US05783593

Reaction notes

Loading…