Dimethylcarbamoyl Chloride → HCID 54349798, compound

HRID 1957358Notes

Reaction equation

HRID 1957358 reaction equation
[CH3:1][N:2]([CH3:6])[C:3](Cl)=[O:4].[N:7]1[CH:12]=[CH:11][CH:10]=[C:9]([CH:13]=[N:14][N:15]2[CH:19]=[N:18][NH:17][C:16]2=[O:20])[CH:8]=1>N1C=CC=CC=1>[CH3:1][N:2]([CH3:6])[C:3]([N:17]1[C:16](=[O:20])[N:15]([N:14]=[CH:13][C:9]2[CH:8]=[N:7][CH:12]=[CH:11][CH:10]=2)[CH:19]=[N:18]1)=[O:4]

Participants

4

Reactant 2

HCID 6598Dimethylcarbamoyl ChlorideHCID 54560653HCID 54560653, compound

Product 1

HCID 54349798HCID 54349798, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

3.2 g of dimethylcarbamoyl chloride are added to a suspension of 3.8 g of 4-(pyridin-3-ylmethyleneamino)-1,2,4-triazol-3-one in 50 ml of pyridine. The resulting solution is stirred for 14 hours at 20° and then concentrated by evaporation. Water is added to the residue. The crystals that have precipitated are filtered off with suction and dried under a high vacuum. 3.6 g of crystals of the title compound having a melting point of 181°-182° are obtained.

Workup

  1. concentrationconcentrated by evaporation
  2. additionWater is added to the residue
  3. customThe crystals that have precipitated
  4. filtrationare filtered off with suction
  5. customdried under a high vacuum
  6. customare obtained

Sources & evidence

ORD record
ord-6daa293bfc534d1abeca111e8331732b
Source dataset
uspto-grants-1998_07
Patent number
US05783704

Reaction notes

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