Hydrogen Bromide → HCID 19598388, compound

HRID 1957403Notes

Reaction equation

HRID 1957403 reaction equation
C([O:8][C:9]([C:11]1[CH:16]=[CH:15][C:14]([N:17]([S:34]([C:37]2[CH:42]=[CH:41][C:40]([CH3:43])=[CH:39][CH:38]=2)(=[O:36])=[O:35])[C:18]([C:20]2[C:21]3[C:26]([N:27]=[C:28]4[C:33]=2[CH:32]=[CH:31][CH:30]=[CH:29]4)=[CH:25][CH:24]=[CH:23][CH:22]=3)=[O:19])=[CH:13][CH:12]=1)=[O:10])C1C=CC=CC=1.[BrH:44]>C(O)(=O)C>[BrH:44].[C:9]([C:11]1[CH:12]=[CH:13][C:14]([N:17]([S:34]([C:37]2[CH:38]=[CH:39][C:40]([CH3:43])=[CH:41][CH:42]=2)(=[O:35])=[O:36])[C:18]([C:20]2[C:33]3[C:28]([N:27]=[C:26]4[C:21]=2[CH:22]=[CH:23][CH:24]=[CH:25]4)=[CH:29][CH:30]=[CH:31][CH:32]=3)=[O:19])=[CH:15][CH:16]=1)([OH:10])=[O:8]

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 19598372HCID 19598372, compound

Product 1

HCID 19598388HCID 19598388, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
60 °C

Procedure

1.17 g (2 mmol) of N-(4-benzyloxycarbonylphenyl)-N-(4-toluenesulfonyl)acridine-9-carboxamide are stirred with 10 ml of 33% strength solution of hydrogen bromide in glacial acetic acid while heating at 60° C. for 4 hours. After cooling, the precipitate is filtered off with suction and dried in vacuo. Yield: 1.00 g (87% of theory)

Workup

  1. temperatureAfter cooling
  2. filtrationthe precipitate is filtered off with suction
  3. customdried in vacuo

Sources & evidence

ORD record
ord-d52cea2220f94c9d882bdf66d1b42e2c
Source dataset
uspto-grants-1998_07
Patent number
US05783696

Reaction notes

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