Dichloromethane → 1-(2-Amino-thiazol-5-ylmethyl)-piperidine-4-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][N:9]([CH2:12][c:13]2[cH:14][n:15][c:16]([NH:18][C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[s:17]2)[CH2:10][CH2:11]1.[Cl:26][CH2:27][Cl:28].[F:29][C:30]([F:31])([F:32])[C:33]([OH:34])=[O:35]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][N:9]([CH2:12][c:13]2[cH:14][n:15][c:16]([NH2:18])[s:17]2)[CH2:10][CH2:11]1Participants
4
Sources & evidence
- ORD record
- ord-fc98f54c8c464b5892f3234d117c9a2f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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