2-(2-Aminobenzoyl)benzoic acid → 5H-Dibenz(b,e)azepine-6,11-dione

HRID 1957628Notes

Reaction equation

HRID 1957628 reaction equation
[CH:1]1[CH:6]=[C:5]([C:7]([C:9]2[C:14]([NH2:15])=[CH:13][CH:12]=[CH:11][CH:10]=2)=[O:8])[C:4]([C:16]([OH:18])=O)=[CH:3][CH:2]=1>C1(C)C(C)=CC=CC=1>[CH:10]1[C:9]2[C:7](=[O:8])[C:5]3[CH:6]=[CH:1][CH:2]=[CH:3][C:4]=3[C:16](=[O:18])[NH:15][C:14]=2[CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 1

HCID 708472-(2-Aminobenzoyl)benzoic acid

Product 1

HCID 708365H-Dibenz(b,e)azepine-6,11-dioneYield 78.7%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A mixture of 2.50 g of 2-aminobenzophenone-2'-carboxylic acid in 50 ml of xylene is stirred at reflux for 23 hours. The mixture is filtered to give 1.82 g of the desired product as a solid.

Workup

  1. temperatureat reflux for 23 hours
  2. filtrationThe mixture is filtered

Sources & evidence

ORD record
ord-2bd661bccb9a4b00bd68cc1e26734bac
Source dataset
uspto-grants-1998_07
Patent number
US05786353

Reaction notes

Loading…