HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Ethyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,2,2-Trichloro-1-(1-methyl-4-nitro-1H-pyrrol-2-yl)ethan-1-one | HCID 2759966 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate | HCID 10442704 | — |
Reaction Steps
0.50 g (1.84 mmol) of 1-methyl-4-nitro-2-trichloroacetyl-1H-pyrrole are initially charged in 5 ml of ethanol, 0.26 ml (1.84 mmol) of triethylamine are added and the mixture is stirred at RT for 2 h. 5 ml of water are added, the reaction mixture is stirred at 0° C. for 30 min and the precipitate is then filtered off with suction and dried under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410090B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-0c3d305414ec4f61836c887c423bf3b0 |
| Source note | uspto-grants-2013_04 |