HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one → 3-(8-Isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydro-pteridin-2-ylamino)-5-nitro-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one | HCID 58405900 | — |
| Reactant | 3-Amino-5-nitrobenzenesulfonamide | HCID 59286191 | — |
| Product | 3-(8-Isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydro-pteridin-2-ylamino)-5-nitro-benzenesulfonamide | HCID 68424302 | 232.1% |
Reaction Steps
Starting from 2-chloro-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one (3.15 g; 4.502 mmol) and 3-amino-5-nitro-benzenesulfonamide (3.49 g; 14.502 mmol), 4.4 g (10.45 mmol; 72% yield) of the desired nitro-product were obtained as a powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410100B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-41b7d4a2f7d24a2ca5bec8667845891f |
| Source note | uspto-grants-2013_04 |