HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxyisonicotinic Acid → N-[5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-1,2-dihydro-2-oxo-4-pyridinecarboxylic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxyisonicotinic Acid | HCID 280756 | — |
| Reactant | 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine | HCID 67281315 | — |
| Product | N-[5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-1,2-dihydro-2-oxo-4-pyridinecarboxylic acid amide | HCID 56961659 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2, 2-trifluoro-ethoxy)-pyridin-3-ylamine and 1,2-dihydro-2-oxo-4-pyridinecarboxylic acid, as starting materials, MS (LC/MS): 424.0 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-de6a1fbe28c34cff90d5a59db03109e7 |
| Source note | uspto-grants-2013_04 |