HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxyisonicotinic Acid → HCID 178422836, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxyisonicotinic Acid | HCID 280756 | — |
| Reactant | 5-(4-Chloro-3-methyl-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine | HCID 67281139 | — |
| Product | HCID 178422836 | HCID 178422836 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 42 g, using 5-(4-Chloro-3-methyl-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (example 57 a) and 1,2-dihydro-2-oxo-4-pyridinecarboxylic acid (CAN 22282-72-0) as starting materials; LC-MS (UV peak area/ESI) 100%, 436.0689 (M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-4f638d787c6642d49d6c982edd48ee20 |
| Source note | uspto-grants-2013_04 |