Benzoic Acid → HCID 56961944, compound

HRID 1958181Notes

Reaction equation

HRID 1958181 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH2:19])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][CH2:16][O:17][CH3:18])=[CH:4][C:3]=1[CH3:20].[C:21](O)(=[O:28])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH:19][C:21](=[O:28])[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH:11]=[N:12][C:13]=2[O:14][CH2:15][CH2:16][O:17][CH3:18])=[CH:4][C:3]=1[CH3:20]

Participants

3

Reactant 2

HCID 243Benzoic AcidHCID 67280473HCID 67280473, compound

Product 1

HCID 56961944HCID 56961944, compound

Procedure

The title compound was synthesized in analogy to Example 42 g, using 5-(4-chloro-3-methyl-phenyl)-6-(2-methoxy-ethoxy)-pyridin-3-ylamine (example 69 c) and benzoic acid as starting materials; LC-MS (UV peak area/ESI) 100%, 397.1307 (M+H)+.

Sources & evidence

ORD record
ord-54287e0887fd4abb92e13ec40bad4fdb
Source dataset
uspto-grants-2013_04
Patent number
US08410107B2

Reaction notes

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