HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylboronic Acid → N-(5-phenyl-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | N-(5-bromo-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide | HCID 67280716 | — |
| Product | N-(5-phenyl-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide | HCID 56961949 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 39, using N-[5-bromo-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-nicotinamide (example G) and B-phenyl-boronic acid (CAN 98-80-6) as starting materials; LC-MS (UV peak area/ESI) 100%, 374.1107 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-732b21510e4b4257a7b00ca36899a0eb |
| Source note | uspto-grants-2013_04 |