HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxynicotinic acid → N-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-5-methoxynicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxynicotinic acid | HCID 4738390 | — |
| Reactant | 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine | HCID 67281315 | — |
| Product | N-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-5-methoxynicotinamide | HCID 56962001 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 42 g, using 5-(4-chloro-phenyl)-6-(2 ,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (example E) and 5-methoxy-3-pyridinecarboxylic acid (CAN 20826-03-3) as starting materials; LC-MS (UV peak area/ESI) 97.8%, 438.0812 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-752e9e1bc81e4af29ce031523ad19afe |
| Source note | uspto-grants-2013_04 |