HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinecarbonyl chloride, hydrochloride (1:1) → N-(5-(4-chlorophenyl)-6-cyclobutoxypyridin-3-yl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinecarbonyl chloride, hydrochloride (1:1) | HCID 88438 | — |
| Reactant | 5-(4-Chloro-phenyl)-6-cyclobutoxy-pyridin-3-ylamine | HCID 67281144 | — |
| Product | N-(5-(4-chlorophenyl)-6-cyclobutoxypyridin-3-yl)nicotinamide | HCID 56962003 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 48e, using 5-(4-chloro-phenyl)-6-cyclobutoxy-pyridin-3-ylamine (example 78 d) and nicotinoyl chloride hydrochloride as starting materials; MS (EI) 380.2(M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-da18aa165d044f9395c5e527bd7bc5ed |
| Source note | uspto-grants-2013_04 |