Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-3-fluorophenylboronic Acid → 5-(4-Chloro-3-fluoro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-3-fluorophenylboronic Acid | HCID 2778656 | — |
| 반응물 | 5-Bromo-6-(2,2,2-trifluoroethoxy)-pyridin-3-ylamine | HCID 67281044 | — |
| 생성물 | 5-(4-Chloro-3-fluoro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine | HCID 67280390 | — |
반응 단계
The title compound was synthesized in analogy to Example E, using 5-bromo-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (example C) and B-(4-chloro-3-fluorophenyl)-boronic acid (CAN 137504-86-0) as starting materials; MS (EI) 379.3 (M+OAc)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08410107B2 |
| 출처 데이터셋 | uspto-grants-2013_04 |
| ORD ID | ord-ecb39ddb23bb4a0397a62b93e9e6afe3 |
| 출처 메모 | uspto-grants-2013_04 |