Ammonium → 4-[2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1H-indole

HRID 195820Notes

Reaction equation

HRID 195820 reaction equation
[C:8]([O:9][C:10](=[O:11])[n:15]1[cH:16][cH:17][c:18]2[c:19](-[c:24]3[c:25]4[n:26]([n:27][c:28]3-[c:29]3[n:30][cH:31][cH:32][cH:33][cH:34]3)[CH2:35][CH2:36][CH2:37]4)[cH:20][cH:21][cH:22][c:23]12)([CH3:12])([CH3:13])[CH3:14].[CH2:42]([Cl:43])[Cl:44].[CH3:38][OH:39].[NH4+:40].[OH-:41].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[nH:15]1[cH:16][cH:17][c:18]2[c:19](-[c:24]3[c:25]4[n:26]([n:27][c:28]3-[c:29]3[n:30][cH:31][cH:32][cH:33][cH:34]3)[CH2:35][CH2:36][CH2:37]4)[cH:20][cH:21][cH:22][c:23]12

Participants

7

Reactant 6

HCID 223AmmoniumHCID 887MethanolHCID 961HydroxideHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 586119614-[2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-indole-1-carboxylic Acid tert-Butyl Ester

Product 1

HCID 103800614-[2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1H-indole

Sources & evidence

ORD record
ord-6f944910ca054ced82bd8a5c89c2ea55
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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