HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-methyl-1,3-oxazole-4-carboxylic Acid → 5-Methyl-oxazole-4-carboxylic acid[5-(4-chloro-phenyl)-6-cyclobutoxy-pyridin-3-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-methyl-1,3-oxazole-4-carboxylic Acid | HCID 11355484 | — |
| Reactant | 5-(4-Chloro-phenyl)-6-cyclobutoxy-pyridin-3-ylamine | HCID 67281144 | — |
| Product | 5-Methyl-oxazole-4-carboxylic acid[5-(4-chloro-phenyl)-6-cyclobutoxy-pyridin-3-yl]-amide | HCID 56962053 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 42 g, using 5-(4-chloro-phenyl)-6-cyclobutoxy-pyridin-3-ylamine (example 78 d) and 5-methyl-4-oxazolecarboxylic acid (CAN 103879-58-9) as starting materials; LC-MS (UV peak area/ESI) 100%, 384.1102 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-2757cdf63a0c4abe9f58f3ba5d6f8c72 |
| Source note | uspto-grants-2013_04 |