HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methylnicotinic acid → N-[5-(4-Chloro-phenyl)-6-cyclobutoxy-pyridin-3-yl]-5-methyl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methylnicotinic acid | HCID 256208 | — |
| Reactant | 5-(4-Chloro-phenyl)-6-cyclobutoxy-pyridin-3-ylamine | HCID 67281144 | — |
| Product | N-[5-(4-Chloro-phenyl)-6-cyclobutoxy-pyridin-3-yl]-5-methyl-nicotinamide | HCID 56962054 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 42 g, using 5-(4-chloro-phenyl)-6-cyclobutoxy-pyridin-3-ylamine (example 78 d) and 5-methyl-3-pyridinecarboxylic acid (CAN 40473-04-9) as starting materials; MS (EI) 394.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-99e675c945744b118f2f5a55e7e8c3c9 |
| Source note | uspto-grants-2013_04 |