HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Methylcarbamoyl)pyridine-3-carboxylic acid → N5-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-N2-methylpyridine-2,5-dicarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Methylcarbamoyl)pyridine-3-carboxylic acid | HCID 15185418 | — |
| Reactant | 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine | HCID 67281315 | — |
| Product | N5-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-N2-methylpyridine-2,5-dicarboxamide | HCID 67280399 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 42 g, using 5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (example E) and 6-[(methylamino)-carbonyl]-3-pyridinecarboxylic acid (CAN 170464-32-1) as starting materials; MS (EI) 465.2(M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410107B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-2ce5973d33514846bc49b2b678bf0c81 |
| Source note | uspto-grants-2013_04 |