Pyruvic Acid → HCID 67281161, compound

HRID 1958209Notes

Reaction equation

HRID 1958209 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH2:20])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:19])([F:18])[F:17])=[CH:4][CH:3]=1.[O:21]=[C:22]([CH3:26])[C:23](O)=[O:24]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[C:10]([NH:20][C:23](=[O:24])[C:22](=[O:21])[CH3:26])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 1060Pyruvic AcidHCID 672813155-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine

Product 1

HCID 67281161HCID 67281161, compound

Procedure

The title compound was synthesized in analogy to Example 42 g, using 5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (example E) and 2-oxo-propanoic acid (127-17-3) as starting materials; MS (EI) 373.0(M+H) +.

Sources & evidence

ORD record
ord-d2a5d3aa6bb742ebb20f9c7c6e28b400
Source dataset
uspto-grants-2013_04
Patent number
US08410107B2

Reaction notes

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