Hydrochloric Acid → HCID 86657901, compound

Participants

Reaction Steps

To a stirred solution of [2-(2-fluoro-ethoxy)-ethyl]-methyl-carbamic acid tert-butyl ester (2.00 g, 0.05 mmol) in dry 1,4-dioxane (20 ml) was added 4M HCl in 1,4-dioxane (22.6 ml, 90 mmol) dropwise at 0° C. The reaction mixture was stirred at RT for 5 h. Volatiles were removed under vacuum. The crude material was washed with hexane and dried under vacuum to give desired product [2-(2-fluoro-ethoxy)-ethyl]-methyl-amine hydrochloride as pale yellow solid (1.2 g, 84%).

Provenance & Evidence