HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58446794, compound → 4-(3-Fluoro-azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid {2-[3-(2-fluoro-ethoxy)-phenyl]imidazo[1,2-a]pyrimidin-7-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58446794 | HCID 58446794 | — |
| Reactant | 4-(3-fluoroazetidine-1-carbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid | HCID 58446796 | — |
| Product | 4-(3-Fluoro-azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid {2-[3-(2-fluoro-ethoxy)-phenyl]imidazo[1,2-a]pyrimidin-7-yl}-amide | HCID 53468243 | — |
Reaction Steps
The title compound was prepared in analogy to example 82 from 2-(3-(2-fluoroethoxy)phenyl)imidazo[1,2-a]pyrimidin-7-amine (120 mg) and 4-(3-fluoroazetidine-1-carbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid (100 mg, 440 μmol). Light brown solid (132 mg, 60%). MS (m/z)=482.2 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410117B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-f9de7b8e908c4c24b70c012b128b88c0 |
| Source note | uspto-grants-2013_04 |