Sodium ion → Benzyl 4-(2-chloro-pyridin-3-yl-amino)-piperidine-1-carboxylate

HRID 195853Notes

Reaction equation

HRID 195853 reaction equation
[C:33]([O:34][BH-:35]([O:36][C:37](=[O:38])[CH3:39])[O:40][C:41](=[O:42])[CH3:43])(=[O:44])[CH3:45].[C:49]([O:50][CH:51]([CH3:52])[CH3:53])(=[O:54])[CH3:55].[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH2:20][C:21](=[O:24])[CH2:22][CH2:23]1.[Cl:25][c:26]1[n:27][cH:28][cH:29][cH:30][c:31]1[NH2:32].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[Na+:46].[Na+:48].[OH-:47]>>[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH2:20][CH:21]([NH:32][c:31]2[c:26]([Cl:25])[n:27][cH:28][cH:29][cH:30]2)[CH2:22][CH2:23]1

Participants

8

Reactant 7

HCID 923Sodium ion2×HCID 961HydroxideHCID 6422Trifluoroacetic acidHCID 7915Isopropyl AcetateHCID 805282-Chloro-3-pyridylamineHCID 643496Benzyl 4-oxopiperidine-1-carboxylateHCID 2724942Triacetoxyborohydride

Product 1

HCID 46853853Benzyl 4-(2-chloro-pyridin-3-yl-amino)-piperidine-1-carboxylate

Sources & evidence

ORD record
ord-0ea46a9982214b5498366b35257f9e5e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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