Pyridine → (4,4-Difluorocyclohexyl)methyl 4-methylbenzenesulfonate

HRID 195854Notes

Reaction equation

HRID 195854 reaction equation
[F:1][C:2]1([F:10])[CH2:3][CH2:4][CH:5]([CH2:8][OH:9])[CH2:6][CH2:7]1.[c:11]1([CH3:21])[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[Cl:20])[cH:15][cH:16]1.[cH:22]1[cH:23][cH:24][n:25][cH:26][cH:27]1>>[F:1][C:2]1([F:10])[CH2:3][CH2:4][CH:5]([CH2:8][O:9][S:17]([c:14]2[cH:13][cH:12][c:11]([CH3:21])[cH:16][cH:15]2)(=[O:18])=[O:19])[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 73974-Toluenesulfonyl chlorideHCID 21184133(4,4-Difluorocyclohexyl)methanol

Product 1

HCID 23224632(4,4-Difluorocyclohexyl)methyl 4-methylbenzenesulfonate

Sources & evidence

ORD record
ord-bf0d5584eedd4caf83f6b995c4796a14
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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