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HRID1958720

反应详情

EQUATION

反应方程式

HRID 1958720 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)c1ccc(-c2ccon2)s1
HCID2797180

5-(1,2-Oxazol-3-yl)thiophene-2-sulfonyl chloride

C7H4ClNO3S2

结构：CN(C)C[C@H](N)CC(=O)OCc1ccccc1
HCID46223508

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)C[C@@H](CC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(-c2ccon2)s1
HCID86641218

未命名化合物

收率 84%

PROCEDURE

实验过程

According to the method described in example S20a, (R)-benzyl 3-amino-4-(dimethylamino)butanoate (27 mg, 0.086 mmol) was reacted with 5-(isoxazol-3-yl)thiophene-2-sulfonyl chloride to yield the title compound as a white solid (38 mg, 84%). MS ESI 450.2 [M+H]+, calcd for [C20H23N3O5S2+H]+ 450.11