HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → (R)-4-(benzyloxy)-2-(4-ethoxy-3-(morpholine-4-carboxamido)phenylsulfonamido)-N,N,N-trimethyl-4-oxobutan-1-aminium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | (R)-benzyl 4-(dimethylamino)-3-(4-ethoxy-3-(morpholine-4-carboxamido)phenyl-sulfonamido)butanoate | HCID 86641228 | — |
| Product | (R)-4-(benzyloxy)-2-(4-ethoxy-3-(morpholine-4-carboxamido)phenylsulfonamido)-N,N,N-trimethyl-4-oxobutan-1-aminium iodide | HCID 68743765 | — |
Reaction Steps
According to the method described in example S72b, (R)-benzyl 4-(dimethylamino)-3-(4-ethoxy-3-(morpholine-4-carboxamido)phenylsulfonamido)butanoate was reacted with methyl iodide to give the title compound as a white solid in quantitative yield. MS ESI 563.3 [M+H]+, calcd for [C27H38N4O7S+H]+ 563.25
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08410150B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-8481927dd76449868f491633da5bf050 |
| Source note | uspto-grants-2013_04 |